Wandin East Road in Wandin East is closed in both directions between Queens Road and Old Baker Road due to a landslip.
Yarra Ranges Council crews will be on-site to assess the issue and direct traffic. Detours will be in place during this time.
This follows previous road closures on the Warburton Highway between Millgrove and Warburton, Old Warburton Road in Wesburn and Monbulk-Seville Road in Wandin East as the Upper Yarra roads continue to suffer from the effects of heavy rain.