Healesville Police are investigating a burglary at the Cellarbrations store in Healesville.
Sergeant Stewart Thomson said that three men smashed the stores front door just after 4am on Wednesday 15 August.
He said they stole a quantity of cigarettes and alcohol and left the scene in a Toyota Landcruiser, which they had parked next to the entrance to the store, in the Coles car park.
The break-in comes two weeks after Healesville BP suffered a similar fate when it was broken into on 3 August.
Sgt Thompson urged people to remain wary and that if anyone saw anything or anyone suspicious in the community to call triple-zero immediately.
Anyone with information is urged to contact Healesville Police on 5962 4422, or to submit a confidential crime report to Crime Stoppers on 1800 333 000 or at www.crimestoppersvic.gov.au.